nucleo相关论文
OBJECTIVE Some mtDNA mutations have been detected in patients with myelodysplastic syndromes(MDSs).As the non-coding reg......
SUMMARY-This article gives a first account on the prehistoric material collected inthe Remedello Museum.In this first w......
A modified spectrophotometric method for coordination nucleo-philic substitution reactions between two kinds of ligands......
Effects of tachyplesin on the morphology and ultrastructure of human gastric carcinoma cell line BGC
AIM To investigate the morphological andultrastructural changes in the human gastriccarcinoma cell line BGC-823 after b......
To investigate whether the polymorphisms of β2-adrenergic receptor (β2-AR) at position 16, 27, 164 are asso-ciated wit......
AIM:To investigate the genetic relationship betweenHirschsprung’s disease(HD)and intestinal neuronaldysplasia(IND)in C......
Aberrant activation of nuclear factor of activated T cell 2 in lamina propria mononuclear cells in u
AIM:To investigate the role of nuclear factor of activated T cell 2(NFAT2),the major NFAT protein in peripheral T cells,......
The development of effective nucleos(t)ide analogs(NAs)against hepatitis B virus(HBV)has improved the outcome of patient......
The immunoregulating effect of Interleukin-1-receptor antagonist (ILlra ) in lupus-like NZB/W F, mice was investigated t......
ve To investigate the existence of the protamine mRNA in sperms of human, rat and mouse
ve To investigate the existenc......
目的:用生物信息学的方法筛选宫颈癌易感基因HLA-DRB1编码区的单核苷酸多态性(coding single nucleo-tide polymorphisms,cSNPs)位......
AIM: To investigate the epigenetic states and expres- sion of imprinted genes in five human embryonic stem cell (hESC) l......
Affinity of anticancer drug,daunomycin,to core histones in solution:comparison of free and cross-lin
Aim:The interaction of anthracycline anticancer drugs with chromatin,nucleo-somes and histone H1 has been extensively s......
This study reports the influence of methyl isopropyl ketone, which often kept in com-mercial zinc dialkyldithiophosphat......
1 Introduction The interactions of metal ions with nucleic acids, nucleosides, and nucleo-bases have been extensively in......
A well-known tumor suppressor, p21, acts parado-xically by promoting tumor growth in some cellular conditions. These con......
目的 观察核苷类药物对不同病毒载量失代偿性乙肝肝硬化患者的抗病毒疗效及安全性.方法 143例患者分为低病毒载量(HBV-DNA......
目的 探讨一种新的摄食调节肽nesfatin-1/NUCB2在人、SD大鼠及ICR小鼠消化系统的分布,为进一步研究其在消化系统的功能奠定形态学......
玉米ZmAGP2基因编码ADP葡萄糖焦磷酸化酶大亚基,参与玉米淀粉的合成途径,从而影响玉米的产量和品质。由多基因控制的玉米的产量性......
用地高辛配基分别标记，制备ＨＰＶ－６、ＨＰＶ－１１、ＨＰＶ－１６及ＨＰＶ－１８的ＤＮＡ探针，应用核酸杂交技术，对３７例宫颈癌活检组织ＤＮＡ作了检测，各型ＨＰＶＤＮＡ的检出率为：ＨＰＶ－６０％、ＨＰＶ－１１２．７、ＨＰＶ－１６６７．５％、ＨＰＶ－１８１３．５％，联合应用ＨＰＶ－１６和ＨＰＶ－１８探针共同检测......
目的探讨环介导等温扩增技术用于检测临床标本乳头瘤病毒HPV18亚型的应用价值。方法设计针对HPV18-L1基因序列中6个区段的4条特异......
本文研究了７，７－二溴双环－「４，１，０」庚烷与二硫代氨基甲酸阴离子在ＤＭＦ中的反应，经光照得到的产物为双取代产物，反应机理涉及ＳＲＮ１过程。......
Influence of a nucleotide oligomerization domain 1 （NOD1） polymorphism and NOD2 mutant alleles on Cr
瞄准：检验核苷酸 oligomerization 领域 1 的基因变化(NOD1 ) 和 NOD2，他们对 Crohn 的疾病的各自的影响显型和基因基因相互作用。方......
肝炎 B (HBV ) 感染仍然是肝细胞的最普通的原因癌和肝肝硬化全世界。最近然而，在 HBV 的理解有相当戏剧的改进联系的肝疾病和它的......
利用PCR技术扩增了伪狂犬病毒湖北株(PRV HB)糖蛋白G(gG)基因,进行了序列测定和分析.结果显示扩增和测序片段长1804bp,G+C含量68.7......
Douglas 冷杉木丛蛾 Orgyia pseudotsugata (鳞翅目：Lymantriidae ) 是 Douglas 冷杉木的经常的除叶剂；在西方的美国的真冷杉木；加拿......
乙型肝炎呈世界性流行,全世界共有3.5～4亿人感染乙型肝炎,其中我国占到全世界患病人数的1/4;每年约有100万人死于HBV感染相关疾病,......
通过自然史研究证明，慢性乙型肝炎(CHB)肝硬化的发生和发展与乙型肝炎病毒(HBV)复制密切相关。临床研究已证实NAs类特别是LAM抑制CH......
目的对于干扰素治疗无效、核苷类似物耐药后停用抗病毒药物治疗的慢性乙型肝炎患者,探讨其停药的后果及再联合应用核苷类似物长期......
目的建立焦磷酸测序（Pyrosequencing,PyroS）法检测HBV反转录酶基因区（rt区）与核苷（酸）类似物（NAs）耐药相关基因突变的检测方法。方法针对HB......
A new preparation method of the N-ethyl 7,17-seco C<sub>19</sub>-diterpenoidalkaloids（5）and（6）by pyrolysis of the N-oxides（3）a......
THE RADICAL NUCLEOPHILIC SUBSTITUTION REACTION OF HETEROCYCLIC KETENE AMINALS WITH 2,4-DINITROHALOBE
The anion of heterocyclic ketene aminals reacted with 2,4-dini-tro-halobenzenes to give an arylated product through the ......
目的:探讨肾癌患者的外周血T淋巴细胞核仁形成区嗜银蛋白(Ag-NORs)的表达特点及其免疫学诊断意义.方法:应用细胞培养银染及KL型肿......
这是作者在刚完稿的《生命进化的物理现》(上海科技出版社即将出版)一书中关于分子序列进化若干观点的综述。这些观点及有关理论结......
4，4’-二（氯甲基）联苯在蒸馏水中受热至回流，40h内未观察到有羟基取代苄基中氯原子的亲核取代反应发生。水中有乙腈存在，该反应就会发生......
根据已发表的禽传染性支气管炎病毒(IBV)Beaudette株核衣壳基因序列,设计了1对特异性引物,采用RTPCR方法,克隆了禽传染性支气管炎......
通过RT-PCR技术从细胞毒液中扩增N蛋白cDNA,克隆至原核表达载体pET-28a（＋）中,所获得的重组质粒pET-28a-N经酶切鉴定正确后,将其转化入......
吉林省延边地区１９９６年６月发生无菌性脑膜脑炎流行，从病人脑脊液和粪便标本中分离到多株病毒，血清学实验证明所分离的病毒为此次无菌性脑膜......
目的探讨氯离子通道阻滞剂5-硝基-2-（3苯丙氨基）苯甲酸（NPPB）在人视网膜色素上皮（RPE）细胞增生中的作用。方法培养人RPE细胞株，ARPE-19细......
Interaction of Boron-Nitrogen Substitued Graphene Nanoribbon with Nucleobases: The Idea of Biosensor
In this paper we have designed a biosensor device built from B-N substituted graphene nanoribbon within density function......
马铃薯卷叶病毒(PLRV)是正链RNA病毒,属黄化病毒组[1]严格虫传,分布广泛,难以控制,侵染马铃薯,给生产造成巨大损失.PLRV基因全长6.......
